Using template literals with the 'new' operator, like new `template`, will throw a SyntaxError. Template literals are not constructors and cannot be used with the 'new' operator. They are a syntax for creating string primitives with special processing for interpolations and multi-line support. When JavaScript encounters a template literal, it processes it according to the template literal rules and produces a string primitive value. Since this is not a constructor function, attempting to use it with 'new' is a syntax error. This is similar to how you cannot use string literals with 'new', such as new 'string', which would also result in a syntax error.